Shut Your Mouth!

And don’t believe everything you think…

Short clip from the end of the film. Henry Fonda is Jack Beauregard:

As a trick or joke it goes back at least to The Odyssey, the Cyclops shouts for help: “Nobody is trying to kill me!”
Then more recently in the Sergio Leone Spaghetti Western, My Name Is Nobody. After the final shootout the inscription on on the loser’s grave marker reads, JACK BEAUREGARD 1848-1899 NOBODY WAS FASTER ON THE DRAW
Here’s a new spin on the meme: “NO gas from the nose and sinuses is inhaled with every breath”

>The discovery within the paranasal sinuses for the production of nitric oxide (NO) has altered the traditional explanations of sinus physiology. This review article reports the ongoing investigation of sinus physiology beginning with the discovery of NO gas production in the paranasal sinuses that occurred in 1995, and the impact that finding has had both in the basic science and clinical arenas. It was shown that healthy paranasal sinus epithelium expresses an inducible NO synthase that continuously generates large amounts of NO, a pluripotent gaseous messenger with potent vasodilating, and antimicrobial activity. This NO can be measured noninvasively in nasally exhaled breath. The role of NO in the sinuses is likely to enhance local host defense mechanisms via direct inhibition of pathogen growth and stimulation of mucociliary activity. The NO concentration in a healthy sinus exceeds those that are needed for antibacterial effects in vitro. In patients with primary ciliary dyskinesia (PCD) and in cystic fibrosis, nasal NO is extremely low. This defect NO generation likely contributes to the great susceptibility to chronic sinusitis in these patients. In addition, the low-nasal NO is of diagnostic value especially in PCD, where nasal NO is very low or absent. Intriguingly, NO gas from the nose and sinuses is inhaled with every breath and reaches the lungs in a more diluted form to enhance pulmonary oxygen uptake via local vasodilation. In this sense NO may be regarded as an “aerocrine” hormone that is produced in the nose and sinuses and transported to a distal site of action with every inhalation. (
More reason to heed George Catlin and Weston Price’s advice to Shut Your Mouth! (breath through your nose)

>There is accumulating evidence that nasal humming (which is the production of a tone without opening the lips or forming words) during nNO measurement increases nNO levels due to a rapid gas exchange in the paranasal sinuses. (

>This suggests that flavones may have anti-gram-negative potential as topical therapeutics when combined with antibiotics or in the context of innate antimicrobials secreted by the respiratory or other epithelia. This may have an additive effect when combined with T2R14-activated NO production. Additional studies are necessary to understand which flavone compounds or mixtures are the most efficacious. (

Put The Lyme In The Coconut

“It’s an ill wind that blows no good”

On the anniversary of Donald Trump’s 2017 inauguration the CDC is reducing their fear-mongering protection racket activities because of the government budget shutdown.

They won’t be able to continue pushing the self-serving and Big Pharma agenda for hyper-vaccination, apocalipstick flu-phobia and general eco-phobia, they won’t be trumpeting the straw man fallacy that people with persistent symptoms after Lyme disease are hypochondriacs because no Borrelia are found.
Fortunately there are Alternative Medicine methods and substances! In medicine as in biology, diversity is strength. Monoculture leads to distress and dysfunction.

Further studies in ceftriaxone-treated infected mice have shown that Borrelia
infections in mice can have a resurgent pattern. The treated mice tested consistently negative for Borrelia through microscopy, culture, xenodiagnoses and PCR from 1 to 8 months after infection.

However, the presence of non-culturable Borrelia was discovered in treated mice 12 months after infection through PCR. At month 12, the levels of Borrelia flaB DNA in the treated mice were similar to the levels found in the saline-treated infected control group.

These results suggest that Borrelia actually replicated after antibiotic removal in a form that is not culturable and that mice may be used as a viable model for long-term treatment study of PTLDS.

The commonly used Lyme antibiotics have been found to be highly effective
against actively growing log phase Borrelia cultures, but have little activity against stationary phase populations.

In order to address this issue, I chose to examine 13 drugs that were orally
bioavailable, had low toxicity, and were previously shown to have high activity against
stationary phase Borrelia populations (<60% viable cells remaining after antibiotic
exposure). These drugs were tested both in double and triple drug combinations in order to study the effects of a combinatorial approach to Borrelia antibiotic treatment.

However, the recommendation against the use of drug combinations for Lyme disease is based primarily on lack of proven efficacy and toxicity concerns, which I have addressed in this study through the use of low toxicity drugs that are frequently used effectively in combination for other diseases.

Methylene blue is the only drug that in the screen with high activity against both
stationary phase and persistent populations. Methylene blue is a photosensitive dye once used as an antimalarial that produces free radicals and hydroxides when exposed to light.

Here, we evaluated the activity of 34 essential oils against B. burgdorferi stationary phase culture as a model for persister bacteria. We found that not all essential oils had activity against the B. burgdorferi stationary phase culture, with top five essential oils (oregano, cinnamon bark, clove bud, citronella, and wintergreen) at a low concentration of 0.25% showing high anti-persister activity that is more active than the known persister drug daptomycin. Interestingly, some highly active essential oils were found to have excellent anti-biofilm ability as shown by their ability to dissolve the aggregated biofilm-like structures. The top three hits, oregano, cinnamon bark, and clove bud completely eradicated all viable cells without any regrowth in subculture in fresh medium, whereas but not citronella and wintergreen did not have this effect.

One MD’s take on Lyme:

“Lyme disease isn’t something that anyone would ever wish for. It changes everyone it touches. It can leave you broken and bitter.

Ten years of my life were robbed by my encounter with chronic Lyme disease. I lost my profession, my social community, and even my passion for life. Everything had to be rebuilt.

Oddly, despite those losses, I’m a better person for having experienced Lyme disease.

Lyme disease is the ultimate teacher. I learned more about overcoming chronic illness in the years I struggled with Lyme disease than I learned in all of medical school and 20 years of medical practice.

I also learned about myself. But it didn’t just happen to me — I had to make it happen for myself.”

Mushing Is Not Skiing

Sleds are not skis.

Tim Alpirod 1

Outside foot on the inside (of the turn radius) runner, inside foot on the ground beyond the inside runner.


I made and sold sleds from 1977 until around 1998. Hundreds of sleds. None of them were laterally flexible. The plastic bed toboggan sleds had aluminum cross brace between the rear stanchions. The Aero sleds with plastic tunnel bed, no wooden parts, aluminum runners, the driving bow was a single piece combination driving bow and stanchions made of aluminum tube or rod. Rigid laterally. If you caught the outside edge/runner it could throw you out or off, but only if your weight was high and you did not shift your weight to lean into turns and side hills. The photos show how. Get Down! Schwarzenegger the actor says in a role in the movies.

With a heavy load, a person or cargo, if the sled runners tilt too easily and the load shifts, it will steer the sled beyond/out of the driver’s control, usually in the wrong direction, sideways down a hill or to the outside of a turn. Positive feedback with negative effects can be catastrophic.

I see many photos of sprint races with traditional basket sleds and newer so-called improved designs that have more sideways flexibility than the pictured Aero sled but the runners are in this same position and the outside runner is partly in the air going around corners on the trail. Because dog sledding is not downhill skiing! The ski instructor tells you to lean into a turn, put your weight on the outside or downhill ski and close the distance between the two skis. The sled runners are a constant distance apart and for mushing you put your weight on the uphill or inside runner. In one of the best mushing videos of my collection, 1993 Alpirod, Deedee is explaining this but got it backwards. “Do as I do, not as I say.” If you lean into a turn which runner will you put your weight on?

This is the best way to balance, to be stable around a corner with a sled having runners 50 cm apart (not like XC or downhill skis that you can bring close together) The exception trail condition is side hill (devers in French) on hard icy surface, or worse, bare pavement. I never encountered this condition in all the years racing in USA and Canada and Alaska and Argentina. In Europe I never encountered this condition except a few times on particular corners in Alpirod, but the rigid sled worked fine.  If you can edge/cant runners on ice you may loose control when you edge too much or hit a bad spot, or if you count on the runner edge and don’t lean into the turn enough. Only one time, last stage of Pirena, mostly it was demonstration for a large spectator crowd on trail that would not be used otherwise, there were hundreds of meters of continuous side hill in very icy conditions.

The sometimes horrifying trails and conditions in Alpirod did drive innovation but only afterward, around 2000, I tried to get a bit more edging with the sled designs, so rarely was it a problem. Then I found it was the attachment of the brake bar that prevented the few degrees of runner edging that would be needed. Using a larger bushing/hole in the mounting bracket 1/8″  or 2-3 mm larger OD than the pin was all that was needed, not an expensive and heavier ball joint. I much prefer simplicity in design and construction.

Ed Moody was a sled builder and musher who understood engineering. Here is a photo of his smaller model named for his daughter, Roz.

Sled Moody Roz

In the Kotzebue sprint race around 1997 there was bare ice on most of the triangle loop trail and strong winds paradoxically seemed to be mostly side winds. None of the sleds worked worth a #!@$. Roxie, Ed Dayton and I stood on the brakes most of the way to keep the line to the dogs tight, otherwise the sled might be perpendicular to the trail. We were so sore could hardly stand up after the race. A slew brake, like a skate edge to bite into the ice, might have helped.

More related:

Solomon’s Seal





And how to use; excerpts from the article below:

>Today, however, few practitioners know how to use Solomon’s Seal anymore. In China, Huangjing never was a component of the classical materia medica (it is not mentioned in either the Shen Nong bencao jing nor the Shanghan lun), but featured prominently in Daoist alchemical texts such as the writings of Ge Hong, Tao Hongjing, and Sun Simiao. Tao Hongjing’s initial introduction of Huangjing in his 6th century Mingyi bielu (An Extraneous Record of Famous Physicians) conveys the typical Daoist flavor that has become associated with the herb since then:

When consumed for long periods of time, Huangjing will cause the body to become weightless, prolong its life span, and alleviate the need to eat food.

Modern biochemical research shows that Huangjing contains a complex array of sugars, starches, vitamins, minerals and antioxidants. At the same time, it has been identified as one of the most effective antifungal agents within the Chinese materia medica. It therefore is not surprising that the ritual imbibing of Huangjing during prolonged periods of fasting and cleansing was once a key component of Daoist hermit practice in China. Over time, many stories developed that enshrouded the medicinal properties of Huangjing in the terms of mythological lore, often associating the herb with the Queen Mother of the West (Xiwangmu), legendary ancestor of Daoist longevity knowledge, or the clairvoyant healer Hua Tuo.

One reason why Huangjing features so prominently in the esoteric arts of nourishing life in China is the pungent flavor* of the unprocessed root, linking it to the concept of yang qi and solar forces. Taiyangcao (Sun Herb) is a common nickname for Huangjing in Daoist folklore, and even its proper name Huangjing can potentially be rendered as “essence of the sun.” The Song dynasty literatus Zhu Qi once exclaimed in a poem composed after being presented with a bottle of Huangjing Wine: “The Sun Herb: nothing more potent in the scrolls of the Immortals for keeping old age at bay!”

A decoction made from processed Huangjing is sweet and nourishing, yet not as rich and sticky as a soup made from Dihuang. It stabilizes blood sugar while exhibiting anti-parasitic qualities, a rare and highly desirable feature among tonic herbs. Ginseng, in contrast, has a tendency to stimulate parasitic activity in people with latent viruses and other chronic pathogens. This particular feature makes Huangjing an excellent candidate for replacing Renshen in ginseng containing prescriptions for people who suffer from chronic fatigue, fibromyalgia and other chronic inflammatory conditions.

Touted as an adaptogenic energy tonic that helps skinny people to gain weight and a blood sugar stabilizer for obese patients who wish to eat less, it is generally stewed with chicken or pork, or immersed in alcohol with other herbs to produce Longevity Wine.

In sum, the recent flurry of Huangjing research attributes the following actions to this ancient Daoist herb:

  • Strengthen physical weakness
  • Stimulate weak digestive function
  • Increase oxygen absorption
  • Increase memory and study focus; reverse developmental issues in children
  • Regulate heart rhythm
  • Decrease elevated cholesterol levels
  • Regulate immune function (increase low WBC count)
  • Regulate blood sugar
  • Counteract fungal infections
  • Benefit the eyes and correct near sightedness

*The Solomon Seal species that grow in North America are not at all pungent.

Another herb related to rat root/calamus/acorus


Tuxedo and Trenchcoat

Hunter T

Recently ran across several studies and analyses about fiber and lung function. Confirms what I first learned feeding flax and psyllium to a dog Trenchcoat (or was it her mother Tuxedo?) who had polyps obstructing in the gut, then seeing the beneficial effects to all the dogs. No more respiratory infections, no kennel cough, no need for the rotten bordetella vaccine. At the time more than 25 years ago people said, how can feeding fiber change the dog’s resistance to infection and congestion in the lungs?

I told Dominique Grandjean, the Alpirod chief vet, about the psyllium husk and it was added to the Royal Canin “sausage” provided to their sponsored teams. There are many proxies, and proxies for proxies, related to prebiotics and health. Butyrate and propionate are sometimes used. A problem that makes many such studies no better than anecdotes for relevance to other situations is that the prebiotics interact with the other foods eaten at the same time and with the specific host individual’s microbiome immediately, initially, and then over a period of many meals. But, to say, the husk of the plantago seed aka psyllium is extremely hydrophilic and forms a viscous mass that probably during passage through the GI tract entrains other food that is not otherwise dietary fiber but reaches the large intestine where effectively it is.

A small amount of certain fiber/prebiotic can have major effects. I was reminded also of  konjac fiber in addition to psyllium/plantain, oats, Aloe vera gel, marshmallow roots and leaves…
>This study provides the first evidence that dietary fiber is independently associated with better lung function and reduced prevalence of COPD.
More on the general subject prebiotics and health:

The general benefit to health of dietary fiber is demonstrated in the results of a longevity study conducted in China, see in an earlier post:

Seize, Crimp, Swage

Tools, fittings and hardware from diverse fields used also for sleds and mushing equipment


Working on the identification and explanation of what’s shown:

Upper level, on yellow plastic, left to right: 1. rolls of sled cables made of steel wire cable (7X7?) coated with black plastic, eyes on the ends swaged with aluminum oval swages (2 such swages are sitting on the larger tool to the right) 2. tool for crimping hose clips/clamps, can also be used on rubber shock cord, 4 such clamps in the middle below, 2 that are ready for use, 2 already clamped tight but with nothing inside 3. multiple opening/size swaging tool used and sold for wire cable aircraft and other applications 4. rubber shock cord hanging down onto the plywood with loop/eye on the end clamped tight/swaged using that tool and thin wall oval sleeve sitting next to the loop/eye (thin wall style oval sleeve in view as purchased was cut to make 2 shorter pieces then cut ends cleaned with wire brush and countersink tool to remove burrs to prevent cut and fray the outer braid on shock cord.

Lower level sitting on plywood bench, left to right: 1. tool for closing/crimping wire clips used on rope and rubber shock cords, red handles 2. wire cable with swaged eyes, oval sleeve/swage covered in heat shrink, center section with white plastic sleeve, used as snow hook/anchor hanger between driving bow stanchions 3. wire clips/rings 4. hose clamps 5. another tool for closing/tightening wire clips or pig rings 6. shock cord with loop on end and full size thin wall oval sleeve.

Sources and suppliers found on the Internet under tools, fittings, hardware, marine, boating, aircraft, cable, ultra-light and combinations of these tags.

The aircraft wire cable tool and fittings and oval sleeves shown were first used to make cable ganglines starting in the 1980s . Then for the single stanchion Aerosled design front and back stay cables.


Sleds Aero

Timo Jokela’s design below:

Sleds Timo1


Dissecting Longevity

Dissecting the Big Data

There is a marvelous phenomenon in Bama county, Guangxi province, China, where the ratio of centenarians was the highest in China. According to the Population Census of China in 2010 [17], there were 80 centenarians in the population of 224,637, reaching to a ratio of 35.6 centenarians per 1 × 105persons [18]. The ratio of centenarians in this region far exceeds the world longevity county standard specified by the United Nations (7.5/100,000) [19]. Nevertheless, few researches have been focused on the metabolites and element profiles of elderly people living in Bama longevous region (LR) because of their traditional and conservative lifestyle.

The study was conducted in the Bama district and Xixiangtang district of the Guangxi province, China, during the period from 2013 to 2015. The Xixiangtang district was selected as the non-longevous region (NLR), where the ratio of centenarians was relatively lower [18] (only three centenarians in the population of 1,156,173 [17], a ratio of 0.26 centenarians per 1 × 105 persons), and the climatic environment was similar with the Bama district.

longevity china nutritents

Longevity Region Centenarians / LR Elderly / Non LRE

Longevity china scfa

Table 3 has some “poke your eye out” differences comparing both LR to NLR

longevity china analysis

Table 4 above and Table 5 below show the relative importance of the variables measured. Table 5 is easier to read and identify the variables such as Total SCFA and specific short chain fatty acids Acetic, Propanoic, Valeric, Butyric, and two minerals, Cobalt and Manganese.

longevity china analysis 2

There were significant differences in acetic acid (p = 0.000), total SCFA (p = 0.000), Mn (p = 0.000), Co (p = 0.000), propionic acid (p = 0.000), butyric acid (p = 0.000) and valeric acid (p = 0.000) among the three groups; the concentrations of these differential components in the LRC group were relatively higher. Therefore, the seven significant differential components could serve as the characteristic components closely related to centenarians from the LR.

There was a significant positive correlation between dietary fiber intake and butyric acid contents in feces, and the correlation coefficient was highest (r = 0.896, p < 0.01). The other short chain fatty acids were also positively associated with dietary fiber intake (p < 0.05). In addition, the contents of the SCFAs were also significantly associated with the intake of energy, protein, vitamin A and nicotinic acid (p < 0.05).

(Nutrient Intake Is Associated with Longevity Characterization by Metabolites and Element Profiles of Healthy Centenarians )

*The lead to this article was a study finding a positive correlation between gut valeric acid and lower Parkinsons and Alzheimers incidence.



Flu Vaccine Dystrophy

Flu Vaccine Paradox

Among the common flaws of so-called “Evidence-Based” Medicine:
*Over-reliance on proxies (antibody titers vs. true performance measures of health and illness) and thereby cherry-picking the criteria to give the desired results
*Reductionist/Mechanistic Arrogance leading to confirmation bias and assumptions that unproven is dis-proven, dismissing alternative hypotheses for which there is no currently known etiology/mechanism

It turns out the 2016-2017 influenza vaccine had “no clear effect” in those between the ages of 18 and 49. Ditto for the elderly. In fact, influenza-related hospitalizations among seniors were the highest they’ve been since the 2014-2015 season, which was rated as “severe.”
>A 2009 U.S. study compared health outcomes for children between 6 months and age 18 who do and do not get annual flu shots and found that children who receive influenza vaccinations have a three times higher risk of influenza-related hospitalization, with asthmatic children at greatest risk.32
>With each successive annual flu vaccination, the theoretical protection from the vaccine appears to diminish.28,29 Research published in 2014 concluded that resistance to influenza-related illness in persons over age 9 years in the U.S. was greatest among those who had NOT received a flu shot in the previous five years.30
>Another 2006 study43 showed that, even though seniors vaccinated against influenza had a 44 percent reduced risk of dying during flu season than unvaccinated seniors, those who were vaccinated were also 61 percent less like to die BEFORE the flu season ever started.
This finding has since been attributed to a “healthy user effect,” the idea of which is that older people who get vaccinated against influenza are already healthier and therefore less likely to die anyway, whereas those who do not get the shot have suffered a decline in health in recent months.
>Statin drugs — taken by 1 in 4 Americans over the age of 45 — may undermine your immune system’s ability to respond to the influenza vaccine.33,34 After vaccination, antibody concentrations were 38 percent to 67 percent lower in statin users over the age of 65, compared to non-statin users of the same age.
( )

The article mentions immune senescence as one possible cause of vaccine ineffectiveness. >A vital immune system is composed of a healthy balance of naive T-cells that attack new invaders and memory T-cells that attack previously known invaders. However, after a naive T-cell attacks a new threat, it becomes a memory T-cell, which will only go after a threat that it remembers.2,3 The result is that the delicate immune balance tips and we have a surplus of memory T-cells and a deficit of naive T-cells. With this imbalance, our body is less able to defend itself against new invasions. This produces a less-vigilant immune system — or immune senescence.4,5 This oral formula of Cistanche tubulosa extract and Reishi mushroom offers tri-mechanism immune support. Cistanche plant extract stimulates the development of naive T-cells for defending against new invaders. Reishi mushroom boosts the function of the innate immune cells, the immune system’s first line defenders. Pu-erh tea is rich in polyphenols and other bioactive compounds to promote bone marrow health, which in turn supports healthy cellular immune function. Taken together, these natural extracts provide a robust, youthful immune response. (

I fixed the link on the blog to the source Mercola site but not yet fixed the reference links to the original research. Regarding conflicting or dueling data, it’s more evidence of cherry-picking proxies. What are the controls, what is the population studied and who is it most relevant to/for, what are the endpoints? I notice a discrepancy in some studies using antibody levels, others confirmed cases of influenza, others influenza cases requiring hospitalization. Who should you trust? No one, but use your own best judgement. I remember getting really really sick from the damn swine flu shot long ago. I remember the results of parainfluenza intranasal kennel cough vaccination in dogs vs. adding psyllium husk to their food, the later being the clear winner. I remember generally most years taking the flu shot I was sick once or twice anyway and some years with no shot I was not sick at all and never as seriously ill as the years when I took the vaccine. What seems most convincing, compelling and actionable to me is the information about immune senescence.

Tobacco Kills!

…Fungus gnats, aphids and other garden pests. Especially seems to be a valuable companion plant for indoor gardening where the absence of UV light and larger predatory insects (like ladybugs) allows some of them to proliferate unchecked.

Woodland Tobacco, Nicotiana sylvestris, an ancestral hardy species, is the best of the Nicotiana genus in my opinion. The sticky resinous leaves attract the pests where they remain to die. Are they immobilized first or absorb some nicotine and other Tobacco pathogens or succumb to a combination of effects? For an indoor gardener it does not matter.


The seeds are small and slow to reach working size. The one tiny plant in the foreground and the two behind are Woodland tobacco. There are already 14 dead fungus gnats on the larger plants.


This tobacco in a quart pot is doing its companion job well. Potted tobaccos can be moved around easily to be positioned beside any plant where aphids or fungus gnats appear. In the top left corner is a leaf from Japanese mugwort, Yomogi. So far no pest insects there but to the right and nearby are French tarragon that seem to be more susceptible.

I have grown a half dozen other Tobacco species. The next two in order of companion plant potentcy are N rustica, “Hopi” Tobacco in some seed catalogs, and N alata, “Jasmine” Tobacco. Hopi Tobacco has large seeds and grows to size faster but also bolts quickly to flower but the flowers don’t amount to much. N alata is slow to bolt, like the Woodland Tobacco, and also like the Woodland species when it does flower has beautiful persistent long trumpet shaped blossoms. Both emit a jasmine fragrance from dusk to dawn.

For a faster start rather than planting only Woodland Tobacco to catch up during the indoor season, an indoor gardener might plant Hopi Tobacco and Woodland Tobacco seeds as early as reasonable before moving or starting other plants indoors. sells seeds of Woodland Tobacco and Hopi Tobacco.

More info about historic and counter-conventional medicinal uses of Tobacco:




The Goldenseal of Approval


“Feets good!” Richard Beck called out to Vi as our two teams passed her stationary beside the snowmobile along the 50 mile trail of the Yellowknife Canadian Championship Dog Derby.

Bronson Beck

Richard Beck used glycerin to protect his dogs’ feet.

At the time of the ’74 Iditarod Preparation H and a copper solution Kopertox were among the treatments to protect and heal sled dog foot problems.

Chilean veterinarian Marcelo Riquelme recommended a commercial product Plastibase derived from a medicinal herb, gotu kola, Centella Asiatica, for skin repair, healing cuts and wounds.

I covered most of the “prior art” here:

Since that article I found two other herbal remedies to recommend, Aloe vera (or other aloes such as more cold-hardy and possibly more potent Aloe arborescens which can be grown as easily as Aloe vera), and Goldenseal, Hydrastis Canadensis. Both can be used as powder or in water.

One of my dogs had an ulcer on the top of the wrist that would not respond to any of the medications I tried over many months. Licking the sore probably contributed to the problem. Finally a Goldenseal root water extract that I made had immediate results. It promotes healing and deters licking because Goldenseal is extremely bitter.

I have used Goldenseal on many other cuts and sores since then. This is the most extreme example:


The photo shows the ulcer already much improved! Because when I first noticed, it looked so bad I was sickened myself to look at it. I thought the bare hip bone was exposed in the area that shows as a deeper and darker scab. So I began to spray the Goldenseal on twice a day.



The sequence covers about one month.